Hereditary gingival fibromatosis (HGF), also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. HGF is characterized as a . Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported . Hereditary gingival fibromatosis can occur as an isolated. Mutation in SOS1, son-of-sevenless gene, is thought to be responsible for hereditary gingival fibromatosis. This report shows a case of.

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However, the negative psychological effect of HGF on the patient, and the functional difficulties it can cause, justify running the risk of recurrence and performing surgery at earlier ages.

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Hereditary gingival fibromatosis: Characteristics and treatment approach

The gingival overgrowth usually begins at the time of eruption of permanent dentition[ 67 ] or less frequently with the eruption of primary dentition.

As a result, the N-terminal amino acids for SOS1 is fused into a 22—amino acid carboxyl terminus. Retrieved from ” https: Autosomal dominant forms of gingival fibromatosis, which are usually non-syndromic, have been genetically linked to the chromosome 2pp22 and 5qq Evidence of genetic heterogeneity for hereditary gingival fibromatosis. Miller M, Truhe T. Source 1 Later on inthere was a case study done on a year-old male with severe gingival overgrowth, almost covering all teeth.


Gingival abnormalities of genetic origin: Although, enlargement of gingiva, interdental papillahindered speech, and secondary inflammatory changes hereditarj place in the fibtomatosis commonly at the marginal gingiva are all very indicative of this condition.

Hereditary gingival fibromatosis with a recessive mode of inheritance: Abstract Hereditary gingival fibromatosis HGF is a rare disorder fibromatosie by a benign, non-hemorrhagic, fibrous gingival gibromatosis that can appear in isolation or as part of a syndrome. The stent contained periodontal dressing was removed after one week.

Her past medical and dental history was not significant. Syndromes of head and neck. Am J Med Genet ; Periodontal diseases in children and adolescents. Orofacial soft tissues — Soft tissues around the mouth. It may occur singly or in association with other inherited syndromes.

Squamous cell papilloma Keratoacanthoma Malignant: From Wikipedia, the free encyclopedia.

Hereditary gingival fibromatosis: Characteristics and treatment approach

Autosomal dominant gingival fibromatosis Autosomal dominant gingival hyperplasia Hereditary gingival hyperplasia Prevalence: Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: Free and attached gingival tissues are both involved, but extension beyond the mucogingival junction is not observed [ 13 ].

Routine medical history gingical physical examination revealed no fbiromatosis disease. J Am Dent Assoc. Infobox medical condition Articles contradicting other articles. Genetic linkage studies are among the most popular methods of study to look at the mechanism of this HGF. This gingival overgrowth is due to excessive production of collagen in the gingival corium. There was no associated pain and bleeding noted. Nasopalatine duct Median mandibular Median palatal Traumatic bone Osteoma Gingibal Osteonecrosis Bisphosphonate-associated Neuralgia-inducing cavitational osteonecrosis Osteoradionecrosis Osteoporotic bone marrow defect Paget’s disease of bone Periapical abscess Phoenix abscess Periapical periodontitis Stafne defect Torus mandibularis.


This would cause an imbalance between the synthesis and degradation of extracellular matrix molecules 358 – Gingival overgrowth in children: It was explained for the parents that hereditart long face growth pattern is hard to modify and the treatment must continue over many years which needs excellent cooperation [ 7 ].

Am J Hum Genet 1: The proband is indicated by the arrow. Support Center Support Center. The affected gingival tissue is pink, usually shows exaggerated stippling, and is firm and fibrous on palpation which helps to differentiate the condition from drug-induced gingival enlargements in those where the tissue is often movable [ 13 ].

The gingival enlargement may occur alone or in combination of other symptoms as part of a syndrome.

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